FMR1 Gene

FMR1 Gene

The FMR1 gene, crucial for making the FMRP protein, impacts synaptic function in neurons. Mutations in the FMR1 gene can lead to Fragile X syndrome, a common cause of inherited intellectual disability. This gene's CGG trinucleotide expansion can silence the gene, nullifying FMRP production and causing severe cognitive impairments.