The Johns Hopkins Antibiotic Guide is an essential resource for clinicians seeking evidence-based recommendations and expert analysis in the field of antimicrobial treatment. Designed to provide comprehensive and up-to-date information, this guide is a valuable tool for healthcare professionals dealing with infectious diseases. The app features hundreds of detailed antimicrobial drug listings, offering in-depth sections on drug forms, dosing, spectrum, resistance, adverse reactions, and interactions. Each entry is crafted to support personalised patient care, ensuring that clinicians have the specialised knowledge needed for optimal treatment outcomes. With expert analysis and commentary on current literature, users can stay informed about the latest developments in antibiotic therapy. Beyond its robust database of drugs, the Johns Hopkins Antibiotic Guide also covers a wide range of disease, pathogen, management, and vaccine topics. This makes it a versatile resource for clinicians who need quick access to reliable information while making critical decisions. Monthly content updates ensure that the guide remains current, reflecting the latest evidence and clinical practices. Integrated into the app is a powerful search function, enabling users to find topics quickly. Features such as bookmarking favourites, highlighting, and note-taking within entries allow for a personalised experience, catering to the individual needs of each clinician. Users also have access to webinars from Johns Hopkins content experts, providing additional learning opportunities and insights. Available for download through various platforms, including Apple and Google Play, the Johns Hopkins Antibiotic Guide offers a convenient solution for busy healthcare professionals. New users can access the guide free for 30 days, after which a one-year subscription is available. This accessibility ensures that clinicians have continuous support in their practice. The app's utility extends beyond antibiotics, with additional guides specialising in psychiatry, HIV, and diabetes. Each guide offers tailored information relevant to the respective fields, maintaining the same high standards of evidence-based recommendations and expert analysis. For instance, the HIV Guide includes topics on diseases, drugs, and management, while the Psychiatry Guide focuses on symptoms, differential diagnoses, treatments, and when to refer. In an era where timely and accurate information is crucial, the Johns Hopkins Antibiotic Guide stands as a critical resource for informed clinical decision-making. By integrating this app into their daily practice, clinicians can enhance their ability to provide personalised, specialised, and evidence-based care.