Familial Encephalopathy With Neuroserpin Inclusion Bodies

Familial Encephalopathy With Neuroserpin Inclusion Bodies

Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is a rare, inherited neurodegenerative disorder. It involves mutations in the neuroserpin gene, causing protein misfolding and accumulation in the brain. Symptoms of familial encephalopathy with neuroserpin inclusion bodies include progressive cognitive decline, seizures, and myoclonus. Diagnosis relies on genetic testing and brain imaging techniques.